Identification of a foetal epigenetic compartment in adult human kidney

The mammalian kidney has extensive repair capacity; however, identifying adult renal stem cells has proven elusive. We applied an epigenetic marker of foetal cell origin (FCO) in diverse human tissues as a probe for developmental cell persistence, finding a 5.4-fold greater FCO proportion in kidney....

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Bibliographic Details
Main Authors: John K. Wiencke, Ze Zhang, Devin C. Koestler, Lucas A. Salas, Annette M. Molinaro, Brock C. Christensen, Karl T. Kelsey
Format: Article
Language:English
Published: Taylor & Francis Group 2022-03-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2021.1900027