Lithium’s effects on therapeutic targets and MRI biomarkers in Parkinson’s disease: A pilot clinical trial

Lithium’s effects on therapeutic targets and MRI biomarkers in Parkinson’s disease: A pilot clinical trial

Background: Lithium has a wide range of neuroprotective actions, has been effective in Parkinson’s disease (PD) animal models and may account for the decreased risk of PD in smokers. Methods: This open-label pilot clinical trial randomized 16 PD patients to “high-dose” (n = 5, lithium carbonate titr...

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Bibliographic Details
Main Authors: Thomas Guttuso, Jr., Rachel Shepherd, Luciana Frick, M. Laura Feltri, Valerie Frerichs, Murali Ramanathan, Robert Zivadinov, Niels Bergsland
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:IBRO Neuroscience Reports
Subjects:
Lithium
Biomarker
Free water
Cognition
Progression
Clinical trial
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242123000398

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http://www.sciencedirect.com/science/article/pii/S2667242123000398

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