Maternal antibody interference contributes to reduced rotavirus vaccine efficacy in developing countries.

Rotavirus (RV) vaccine efficacy is significantly reduced in lower- and middle-income countries (LMICs) compared to high-income countries. This review summarizes current research into the mechanisms behind this phenomenon, with a particular focus on the evidence that maternal antibody (matAb) interfe...

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Bibliographic Details
Main Authors: Claire E Otero, Stephanie N Langel, Maria Blasi, Sallie R Permar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009010