Identification of an endogenous retroviral signature to predict anti-PD1 response in advanced clear cell renal cell carcinoma: an integrated analysis of three clinical trials

Background: Endogenous retrovirus (ERV) elements are genomic footprints of ancestral retroviral infections within the human genome. Previous studies have demonstrated that dysregulated ERV transcription level is associated with immune cell infiltration in cancers, but the association between ERV exp...

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Bibliographic Details
Main Authors: Jian-Guo Zhou, Yu Zeng, Haitao Wang, Su-Han Jin, Yun-Jia Wang, Sisi He, Benjamin Frey, Rainer Fietkau, Markus Hecht, Hu Ma, Wenchuan Zhang, Udo S. Gaipl
Format: Article
Language:English
Published: SAGE Publishing 2022-09-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359221126154