Synthesis of the Enantiomers of Thioridazine

Synthesis of the Enantiomers of Thioridazine

Abstract Thioridazine, a well-known antipsychotic drug, has shown promising effects on several bacterial strains (including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus). Suppressive effects towards selected cancer cell-lines have also been reported. However, due to adv...

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Bibliographic Details
Main Authors: Simen Antonsen, Erling B. Monsen, Kirill Ovchinnikov, Jens M. J. Nolsøe, Dag Ekeberg, Jette E. Kristiansen, Dzung B. Diep, Yngve Stenstrøm
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2020-01-01
Series:SynOpen
Subjects:
thioridazine
antibacterial
enantiomers
total synthesis
sulfinyl aldimines
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1690834

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1690834

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