RalGPS2 Interacts with Akt and PDK1 Promoting Tunneling Nanotubes Formation in Bladder Cancer and Kidney Cells Microenvironment

RalGPS2 Interacts with Akt and PDK1 Promoting Tunneling Nanotubes Formation in Bladder Cancer and Kidney Cells Microenvironment

RalGPS2 is a Ras-independent Guanine Nucleotide Exchange Factor for RalA GTPase that is involved in several cellular processes, including cytoskeletal organization. Previously, we demonstrated that RalGPS2 also plays a role in the formation of tunneling nanotubes (TNTs) in bladder cancer 5637 cells....

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Bibliographic Details
Main Authors: Alessia D’Aloia, Edoardo Arrigoni, Barbara Costa, Giovanna Berruti, Enzo Martegani, Elena Sacco, Michela Ceriani
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
tunneling nanotubes
bladder cancer
kidney
microenvironment
stress condition
RalGPS2
Online Access:https://www.mdpi.com/2072-6694/13/24/6330

Internet

https://www.mdpi.com/2072-6694/13/24/6330

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