Sphingosine 1 phosphate promotes hypertension specific memory T cell trafficking in response to repeated hypertensive challenges

Sphingosine 1 phosphate promotes hypertension specific memory T cell trafficking in response to repeated hypertensive challenges

We have previously shown that effector memory (TEM) cells accumulate in the bone marrow (BM) and the kidney in response to l-NAME/high salt challenge. It is not well understood if measures to block the exodus of that effector memory cells prevent redistribution of these cells and protect from hypert...

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Bibliographic Details
Main Authors: Maha M. Itani, Hala Jarrah, Dina Maaliki, Zeina Radwan, Rima Farhat, Hana A. Itani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Physiology
Subjects:
inflammation
memory T cells
S1PR1
memory T-lymphocytes trafficking
kidney
hypertension
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.930487/full

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https://www.frontiersin.org/articles/10.3389/fphys.2022.930487/full

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