NMDAR-mediated modulation of gap junction circuit regulates olfactory learning in C. elegans
Neural plasticity underlies learning and is regulated by modulation of gap junctions. Here, the authors show that NMDAR- and CaMKII-mediated cell autonomous downregulation of gap junction molecules in a circuit of interneurons facilitates olfactory learning affecting behavior in C. elegans.
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-07-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-17218-0 |