NMDAR-mediated modulation of gap junction circuit regulates olfactory learning in C. elegans

Neural plasticity underlies learning and is regulated by modulation of gap junctions. Here, the authors show that NMDAR- and CaMKII-mediated cell autonomous downregulation of gap junction molecules in a circuit of interneurons facilitates olfactory learning affecting behavior in C. elegans.

Bibliographic Details
Main Authors: Myung-Kyu Choi, He Liu, Taihong Wu, Wenxing Yang, Yun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17218-0