High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy

High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy

Summary: Peanut allergy can result in life-threatening reactions and is a major public health concern. Oral immunotherapy (OIT) induces desensitization to food allergens through administration of increasing amounts of allergen. To dissect peanut-specific immunoglobulin E (IgE) and IgG responses in s...

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Bibliographic Details
Main Authors: Genghao Chen, Ellen L. Shrock, Mamie Z. Li, Jonathan M. Spergel, Kari C. Nadeau, Jacqueline A. Pongracic, Dale T. Umetsu, Rima Rachid, Andrew J. MacGinnitie, Wanda Phipatanakul, Lynda Schneider, Hans C. Oettgen, Stephen J. Elledge
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Cell Reports Medicine
Subjects:
peanut allergy
antibody
antibody repertoire
phage display
oral immunotherapy
food allergy
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121002688

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http://www.sciencedirect.com/science/article/pii/S2666379121002688

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