ESCRT-independent budding of HIV-1 gag virus-like particles from Saccharomyces cerevisiae spheroplasts.

ESCRT-independent budding of HIV-1 gag virus-like particles from Saccharomyces cerevisiae spheroplasts.

Heterologous expression of HIV-1 Gag in a variety of host cells results in its packaging into virus-like particles (VLPs) that are subsequently released into the extracellular milieu. This phenomenon represents a useful tool for probing cellular factors required for viral budding and has contributed...

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Bibliographic Details
Main Authors: Andrew P Norgan, Jacqueline R E Lee, Andrea J Oestreich, Johanna A Payne, Eugene W Krueger, David J Katzmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528670?pdf=render

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http://europepmc.org/articles/PMC3528670?pdf=render

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