Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the <it>TP53 </it>locus

<p>Abstract</p> <p>Background</p> <p>Together single nucleotide substitutions and small insertion/deletion variants are the most common form of sequence variation in the human gene pool.</p> <p>High-resolution SNP profile and/or haplotype analyses enable the...

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Bibliographic Details
Main Authors: De Silva Deepika, Le Calvez-Kelm Florence, Nguyen-Dumont Tú, Voegele Catherine, Gemignani Federica, Garritano Sonia, Lesueur Fabienne, Landi Stefano, Tavtigian Sean V
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/10/5