Heterogeneity in leukemia cells that escape drug-induced senescence-like state

Heterogeneity in leukemia cells that escape drug-induced senescence-like state

Abstract Erythropoietin (EPO) suppresses drug-induced apoptosis in EPO-receptor-positive leukemia cells and allows cells to persist after drug treatment by promoting cellular senescence. Importantly a small proportion of senescent cells can re-enter the cell cycle and resume proliferation after drug...

Full description

Bibliographic Details
Main Authors: David Miller, Kyra Kerkhofs, Farnoosh Abbas-Aghababazadeh, Sahib Singh Madahar, Mark D. Minden, Josée Hébert, Benjamin Haibe-Kains, Mark A. Bayfield, Samuel Benchimol
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06015-4

Internet

https://doi.org/10.1038/s41419-023-06015-4

Similar Items