Lactate activates CCL18 expression via H3K18 lactylation in macrophages to promote tumorigenesis of ovarian cancer

Lactate activates CCL18 expression via H3K18 lactylation in macrophages to promote tumorigenesis of ovarian cancer

This study investigates the role of lactate in the genesis and progression of ovarian cancer (OV) and explores the underlying mechanisms. Serum lactate levels show a positive correlation with tumor grade and poor prognosis in patients with OV. Bioinformatics analysis identifies...

Full description

Bibliographic Details
Main Authors: Sun Jinrui, Feng Qinmei, He Yue, Wang Ming, Wu Yumei
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-07-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
ovarian cancer
lactate
macrophage
CCL18
lactylation
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024111

Internet

https://www.sciengine.com/doi/10.3724/abbs.2024111

Similar Items