Leukocyte- and platelet-rich fibrin in endoscopic endonasal skull base reconstruction: study protocol for a multicenter prospective, parallel-group, single-blinded randomized controlled non-inferiority trial

Leukocyte- and platelet-rich fibrin in endoscopic endonasal skull base reconstruction: study protocol for a multicenter prospective, parallel-group, single-blinded randomized controlled non-inferiority trial

Abstract Background Recent advances in endoscopic endonasal transsphenoidal approaches (EETA) for skull base lesions have resulted in a significant increase in extent and complexity of skull base defects, demanding more elaborate and novel reconstruction techniques to prevent cerebrospinal fluid (CS...

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Bibliographic Details
Main Authors: Birgit Coucke, Anaïs Van Hoylandt, Mark Jorissen, Jeroen Meulemans, Thomas Decramer, Johannes van Loon, Vincent Vander Poorten, Tom Theys, Laura Van Gerven
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Trials
Subjects:
Cerebrospinal fluid leakage
Endoscopic endonasal transsphenoidal approach
Dura
Regenerative medicine
Skull base
Prevention
Online Access:https://doi.org/10.1186/s13063-023-07492-w

Internet

https://doi.org/10.1186/s13063-023-07492-w

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