Genetic dissection of intratumor heterogeneity of PD‐L1 expression in EGFR‐mutated lung adenocarcinoma

Genetic dissection of intratumor heterogeneity of PD‐L1 expression in EGFR‐mutated lung adenocarcinoma

Abstract In this study, we investigated the association between PD‐L1 expression in tumor cells and underlying genetic mutations, which was analyzed in detail using laser microdissection and next‐generation sequencing analysis. To investigate whether driver mutations are involved in the background o...

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Bibliographic Details
Main Authors: Kei Kunimasa, Yosuke Hirotsu, Kenji Amemiya, Keiichiro Honma, Harumi Nakamura, Kazumi Nishino, Masao Omata
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Thoracic Cancer
Subjects:
EGFR mutation
intratumor heterogeneity
PD‐L1 expression
tumor infiltrating lymphocytes
Online Access:https://doi.org/10.1111/1759-7714.15038

Internet

https://doi.org/10.1111/1759-7714.15038

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