Lichen-Derived Depsides and Depsidones Modulate the Nrf2, NF-κB and STAT3 Signaling Pathways in Colorectal Cancer Cells

Lichen-Derived Depsides and Depsidones Modulate the Nrf2, NF-κB and STAT3 Signaling Pathways in Colorectal Cancer Cells

The study aimed to evaluate the possible modulation of Nrf2, NF-ĸB and STAT3 signaling pathways in the colorectal cancer (CRC) cells line DLD-1 and HCT116 by secondary metabolites of lichens. An attempt was made to indicate the most promising targets in these signaling pathways. Attention was also p...

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Bibliographic Details
Main Authors: Katarzyna Papierska, Violetta Krajka-Kuźniak, Jarosław Paluszczak, Robert Kleszcz, Marcin Skalski, Elżbieta Studzińska-Sroka, Wanda Baer-Dubowska
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
colorectal cancer
lichens
NF-κB
Nrf2
STAT3
Online Access:https://www.mdpi.com/1420-3049/26/16/4787

Internet

https://www.mdpi.com/1420-3049/26/16/4787

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