Transcriptomics and systems biology identify non-antibiotic drugs for the treatment of ocular bacterial infection

Summary: Increasing antibiotic resistance among ocular pathogens often results in treatment failure for blinding infections such as endophthalmitis. Hence, newer therapeutics is needed to combat multidrug-resistant infections. Here, we show a drug repurposing approach using a connectivity map based...

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Bibliographic Details
Main Authors: Susmita Das, Sukhvinder Singh, Sarthak Satpathy, Manoj Bhasin, Ashok Kumar
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222011348