Mitochondrial Unfolded Protein Response Gene <i>Clpp</i> Is Required for Oocyte Function and Female Fertility

Mitochondrial Unfolded Protein Response Gene <i>Clpp</i> Is Required for Oocyte Function and Female Fertility

Mitochondrial unfolded protein stress response (mtUPR) plays a critical role in regulating cellular and metabolic stress response and helps maintain protein homeostasis. Caseinolytic peptidase P (CLPP) is one of the key regulators of mtUPR and promotes unfolded protein degradation. Previous studies...

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Bibliographic Details
Main Authors: Yagmur Ergun, Aysegul Gizem Imamoglu, Mauro Cozzolino, Cem Demirkiran, Murat Basar, Akanksha Garg, Raziye Melike Yildirim, Emre Seli
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial stress response
mitochondrial dysfunction
female fertility
oocyte function
CLPP
Online Access:https://www.mdpi.com/1422-0067/25/3/1866

Internet

https://www.mdpi.com/1422-0067/25/3/1866

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