Drug-Eluting Biodegradable Implants for the Sustained Release of <i>Bis</i>phosphonates

Despite being one of the first-line treatments for osteoporosis, the <i>bis</i>phosphonate drug class exhibits an extremely low oral bioavailability (<1%) due to poor absorption from the gastrointestinal tract. To overcome this, and to explore the potential for sustained drug release,...

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Bibliographic Details
Main Authors: Cintya Dharmayanti, Todd A. Gillam, Desmond B. Williams, Anton Blencowe
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/12/2930