Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine

Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine

Long-term use of olanzapine, an antipsychotic drug, induces hypertriglyceridemia, resulting in a higher risk of cardiovascular disease. However, the effects and underlying mechanisms of short-term use of olanzapine on circulating triglyceride levels remain poorly understood. Here, the role of apolip...

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Bibliographic Details
Main Authors: Piao-Piao Huang, Wen-Qiang Zhu, Jing-Mei Xiao, Yi-Qi Zhang, Rong Li, Yang Yang, Li Shen, Fei Luo, Wen Dai, Ping-An Lian, Ya-Xin Tang, Juan-Li Ran, Xian-Sheng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
olanzapine
hypertriglyceridemia
apolipoprotein A5
sorting
secretion
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.935362/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.935362/full

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