Multidrug Resistance in <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content>: Identification of Functionally Important Residues in the MtrD Efflux Protein

ABSTRACT A key mechanism that Neisseria gonorrhoeae uses to achieve multidrug resistance is the expulsion of structurally different antimicrobials by the MtrD multidrug efflux protein. MtrD resembles the homologous Escherichia coli AcrB efflux protein with several common structural features, includi...

Full description

Bibliographic Details
Main Authors: Mohsen Chitsaz, Lauren Booth, Mitchell T. Blyth, Megan L. O’Mara, Melissa H. Brown
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02277-19