Schnurri-3 drives tumor growth and invasion in cancer cells expressing interleukin-13 receptor alpha 2

Abstract Interleukin 13 receptor alpha 2 (IL13Rα2) is a relevant therapeutic target in glioblastoma (GBM) and other tumors associated with tumor growth and invasion. In a previous study, we demonstrated that protein tyrosine phosphatase 1B (PTP1B) is a key mediator of the IL-13/IL13Rα2 signaling pat...

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Bibliographic Details
Main Authors: Rubén A. Bartolomé, Ángela Martín-Regalado, Laura Pintado-Berninches, Javier Robles, Mª Ángeles Ramírez-González, Issam Boukich, Pilar Sanchez-Gómez, Irina V. Balyasnikova, J. Ignacio Casal
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06255-4