Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

Abstract Background It is known that the medicinal herb Alpinia oxyphylla Miq. is widely used as a remedy for diarrhea as well as the symptoms accompanying hypertension and cerebrovascular disorders. Moreover, it has also been reported that Alpinia oxyphylla Miq. has beneficial effects on anti-senes...

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Bibliographic Details
Main Authors: Yung-Ming Chang, Hen-Hong Chang, Chin-Chuan Tsai, Hung-Jen Lin, Tsung-Jung Ho, Chi-Xin Ye, Ping-Ling Chiu, Yueh-Sheng Chen, Ray-Jade Chen, Chih-Yang Huang, Chien-Chung Lin
Format: Article
Language:English
Published: BMC 2017-03-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Alpinia oxyphylla Miq. fruit extract
IGF-1
nerve regeneration
proliferation
RSC96 Schwann cell
Online Access:http://link.springer.com/article/10.1186/s12906-017-1695-2

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http://link.springer.com/article/10.1186/s12906-017-1695-2

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