The P2X7 Receptor Is Involved in Diabetic Neuropathic Pain Hypersensitivity Mediated by TRPV1 in the Rat Dorsal Root Ganglion

The P2X7 Receptor Is Involved in Diabetic Neuropathic Pain Hypersensitivity Mediated by TRPV1 in the Rat Dorsal Root Ganglion

The purinergic 2X7 (P2X7) receptor expressed in satellite glial cells (SGCs) is involved in the inflammatory response, and transient receptor potential vanilloid 1 (TRPV1) participates in the process of neurogenic inflammation, such as that in diabetic neuropathic pain (DNP) and peripheral neuralgia...

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Bibliographic Details
Main Authors: Anhui Wang, Xiangchao Shi, Ruoyang Yu, Bao Qiao, Runan Yang, Changshui Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
diabetic neuropathic pain
P2X7 receptors
TRPV1
dorsal root ganglion
satellite glial cells
neurons
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.663649/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2021.663649/full

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