Metagenomic Analyses Reveal Distinct Gut Microbiota Signature for Predicting the Neoadjuvant Chemotherapy Responsiveness in Breast Cancer Patients

Metagenomic Analyses Reveal Distinct Gut Microbiota Signature for Predicting the Neoadjuvant Chemotherapy Responsiveness in Breast Cancer Patients

BackgroundGrowing evidence supports the modulatory role of human gut microbiome on neoadjuvant chemotherapy (NAC) efficacy. However, the relationships among the gut microbiome, tumor-infiltrating lymphocytes (TILs), and NAC response for breast cancer (BC) patients remain unclear. We thus proposed th...

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Bibliographic Details
Main Authors: Yuanyuan Li, Bingbin Dong, Wei Wu, Jiawei Wang, Hao Jin, Kangmei Chen, Kangling Huang, Songyin Huang, Yandan Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
gut microbiota
breast cancer
neoadjuvant chemotherapy
pathologic response
CD4+ T lymphocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.865121/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.865121/full

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