Lifespan extension in a semelparous chordate occurs via developmental growth arrest just prior to meiotic entry.

It is proposed that the ageing process is linked to signaling from the germline such that the rate of ageing can be adjusted to the state of the reproductive system, allowing these two processes to co-evolve. Mechanistic insight into this link has been primarily derived from iteroparous reproductive...

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Bibliographic Details
Main Authors: Gunasekaran Subramaniam, Coen Campsteijn, Eric M Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3973624?pdf=render