Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic‐guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model

Abstract Enflicoxib is a newly developed NSAID of the coxib class. The optimal therapeutic dose to be confirmed in the field studies was established using a combination of pharmacokinetic (PK) modelling and pharmacodynamic (PD) studies. First, a PK study was performed to determine the plasmatic prof...

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Bibliographic Details
Main Authors: Josep‐Maria Cendrós, Marta Salichs, Gregorio Encina, Jose Miguel Vela, Josep M. Homedes
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Veterinary Medicine and Science
Subjects:
Online Access:https://doi.org/10.1002/vms3.670