BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production.

BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production.

BACKGROUND: Leishmania braziliensis is the main causative agent of cutaneous leishmaniasis in Brazil. Protection against infection is related to development of Th1 responses, but the mechanisms that mediate susceptibility are still poorly understood. Murine models have been the most important tools...

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Bibliographic Details
Main Authors: Diego L Costa, Vanessa Carregaro, Djalma S Lima-Júnior, Neide M Silva, Cristiane M Milanezi, Cristina R Cardoso, Ângela Giudice, Amélia R de Jesus, Edgar M Carvalho, Roque P Almeida, João S Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3046967?pdf=render

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http://europepmc.org/articles/PMC3046967?pdf=render

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