Rad51 inhibits translocation formation by non-conservative homologous recombination in Saccharomyces cerevisiae.

Chromosomal translocations are a primary biological response to ionizing radiation (IR) exposure, and are likely to result from the inappropriate repair of the DNA double-strand breaks (DSBs) that are created. An abundance of repetitive sequences in eukaryotic genomes provides ample opportunity for...

Full description

Bibliographic Details
Main Authors: Glenn M Manthey, Adam M Bailis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2912366?pdf=render