Direct comparison of canine and human immune responses using transcriptomic and functional analyses

Abstract The canine spontaneous cancer model is increasingly utilized to evaluate new combined cancer immunotherapy approaches. While the major leukocyte subsets and phenotypes are closely related in dogs and humans, the functionality of T cells and antigen presenting cells in the two species has no...

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Bibliographic Details
Main Authors: Lyndah Chow, William Wheat, Dominique Ramirez, Renata Impastato, Steven Dow
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50340-9