Structural determinants of voltage-gating properties in calcium channels

Structural determinants of voltage-gating properties in calcium channels

Voltage-gated calcium channels control key functions of excitable cells, like synaptic transmission in neurons and the contraction of heart and skeletal muscles. To accomplish such diverse functions, different calcium channels activate at different voltages and with distinct kinetics. To identify th...

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Bibliographic Details
Main Authors: Monica L Fernández-Quintero, Yousra El Ghaleb, Petronel Tuluc, Marta Campiglio, Klaus R Liedl, Bernhard E Flucher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
CaV1.1
voltage sensing
voltage-gated calcium channel
resting state structure
molecular dynamics simulation
Online Access:https://elifesciences.org/articles/64087

Internet

https://elifesciences.org/articles/64087

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