H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks

H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks

Background: Transposons are selfish genetic elements that self-reproduce in host DNA. They were active during evolutionary history and now occupy almost half of mammalian genomes. Close insertions of transposons reshaped structure and regulation of many genes considerably. Co-evolution of transposon...

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Bibliographic Details
Main Authors: Anna A. Igolkina, Arsenii Zinkevich, Kristina O. Karandasheva, Aleksey A. Popov, Maria V. Selifanova, Daria Nikolaeva, Victor Tkachev, Dmitry Penzar, Daniil M. Nikitin, Anton Buzdin
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
human genome molecular evolution
histone modifications
transposable elements
retrotransposons
molecular pathway analysis
gene ontology
epigenetics
gene regulation
promoter
chromatin structure
Online Access:https://www.mdpi.com/2073-4409/8/9/1034

Internet

https://www.mdpi.com/2073-4409/8/9/1034

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