Tctp regulates the level and localization of Foxo for cell growth in Drosophila

Abstract Regulation of cell size is crucial for organ development. Insulin signaling regulates organ size by antagonizing the subgroup O of forkhead box transcription factor (Foxo) through 14-3-3 in Drosophila. However, mechanisms for controlling the level and the nuclear localization of Foxo in dev...

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Bibliographic Details
Main Authors: Sujin Nam, Thao Phuong Le, SeYeon Chung, Kwang-Wook Choi
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00937-2