A mechanism with severing near barbed ends and annealing explains structure and dynamics of dendritic actin networks

Single molecule imaging has shown that part of actin disassembles within a few seconds after incorporation into the dendritic filament network in lamellipodia, suggestive of frequent destabilization near barbed ends. To investigate the mechanisms behind network remodeling, we created a stochastic mo...

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Bibliographic Details
Main Authors: Danielle Holz, Aaron R Hall, Eiji Usukura, Sawako Yamashiro, Naoki Watanabe, Dimitrios Vavylonis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/69031