Mechanical interaction between actin cytoskeleton and nucleus regulates intracellular YAP localization in osteogenic differentiation in human mesenchymal stem cells.

Mechanotransduction, in which mechanical forces and deformations are converted into biochemical signals to change gene expression, is critical for directing the differentiation of mesenchymal stem cells. A number of studies have indicated that a transcriptional regulator, yes-associated protein (YAP...

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Bibliographic Details
Main Authors: Masashi YAMAZAKI, Hiromichi FUJIE, Hiromi MIYOSHI
Format: Article
Language:Japanese
Published: The Japan Society of Mechanical Engineers 2020-10-01
Series:Nihon Kikai Gakkai ronbunshu
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/transjsme/86/890/86_20-00264/_pdf/-char/en