Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study

Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study

Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the clinical practice. Unfortunately, together with analgesia, a number of adverse effects can occur such as nausea, vomiting, constipation, gastrointestinal alterations and cognitive i...

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Bibliographic Details
Main Authors: Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Lucarini, Carmen Parisio, Alessandra Toti, Bruno Fiorentino, Maria Adele Rigamonti, Laura Calosi, Carla Ghelardini
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
intranasal delivery
morphine
naltrexone
opioids side effects
oxycodone
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.576624/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.576624/full

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