Small vessel cerebrovascular disease is associated with cognition in prospective Alzheimer’s clinical trial participants

Small vessel cerebrovascular disease is associated with cognition in prospective Alzheimer’s clinical trial participants

Abstract Background Secondary prevention clinical trials for Alzheimer’s disease (AD) target amyloid accumulation in asymptomatic, amyloid-positive individuals, but it is unclear to what extent other pathophysiological processes, such as small vessel cerebrovascular disease, account for participant...

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Bibliographic Details
Main Authors: Clarissa D. Morales, Dejania Cotton-Samuel, Patrick J. Lao, Julia F. Chang, Jeffrey D. Pyne, Mohamad J. Alshikho, Rafael V. Lippert, Kelsang Bista, Christiane Hale, Natalie C. Edwards, Kay C. Igwe, Kacie Deters, Molly E. Zimmerman, Adam M. Brickman
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
White matter hyperintensities
Amyloid
Alzheimer’s disease
Clinical trial
Online Access:https://doi.org/10.1186/s13195-024-01395-x

Internet

https://doi.org/10.1186/s13195-024-01395-x

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