Human in vivo evidence of associations between herpes simplex virus and cerebral amyloid-beta load in normal aging

Abstract Background Mounting data suggests that herpes simplex virus type 1 (HSV-1) is involved in the pathogenesis of AD, possibly instigating amyloid-beta (Aβ) accumulation decades before the onset of clinical symptoms. However, human in vivo evidence linking HSV-1 infection to AD pathology is lac...

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Bibliographic Details
Main Authors: Jose L. Cantero, Mercedes Atienza, Isabel Sastre, María Jesús Bullido
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13195-024-01437-4