Human in vivo evidence of associations between herpes simplex virus and cerebral amyloid-beta load in normal aging
Abstract Background Mounting data suggests that herpes simplex virus type 1 (HSV-1) is involved in the pathogenesis of AD, possibly instigating amyloid-beta (Aβ) accumulation decades before the onset of clinical symptoms. However, human in vivo evidence linking HSV-1 infection to AD pathology is lac...
Main Authors: | Jose L. Cantero, Mercedes Atienza, Isabel Sastre, María Jesús Bullido |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-04-01
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Series: | Alzheimer’s Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13195-024-01437-4 |
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