Restoration of Developmental Competence in Low-Quality Porcine Cumulus–Oocyte Complexes through the Supplementation of Sonic Hedgehog Protein during In Vitro Maturation

The sonic hedgehog (SHH) pathway is an important signaling pathway for mammalian ovarian folliculogenesis and oocyte maturation. A previous study demonstrated that low-quality porcine cumulus–oocyte complexes (COCs) have low developmental competence, with lower SHH signaling protein expression befor...

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Bibliographic Details
Main Authors: Pil-Soo Jeong, Hyo-Gu Kang, Bong-Seok Song, Sun-Uk Kim, Bo-Woong Sim, Sanghoon Lee
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/13/6/1001