Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

<p>Abstract</p> <p>Background</p> <p>Glutaminyl cyclase (QC) forms the pyroglutamyl residue at the amino terminus of numerous secretory peptides and proteins. We previously proposed the mammalian QC has some features in common with zinc aminopeptidases. We now have gene...

Full description

Bibliographic Details
Main Authors: Misquitta Stephanie A, Lovell Simon C, Booth Rachell E, Bateman Robert C
Format: Article
Language:English
Published: BMC 2004-02-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/2/2