Decreasing Phosphatidylcholine on the Surface of the Lipid Droplet Correlates with Altered Protein Binding and Steatosis

Decreasing Phosphatidylcholine on the Surface of the Lipid Droplet Correlates with Altered Protein Binding and Steatosis

Alcoholic fatty liver disease (AFLD) is characterized by an abnormal accumulation of lipid droplets (LDs) in the liver. Here, we explore the composition of hepatic LDs in a rat model of AFLD. Five to seven weeks of alcohol consumption led to significant increases in hepatic triglyceride mass, along...

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Bibliographic Details
Main Authors: Laura Listenberger, Elizabeth Townsend, Cassandra Rickertsen, Anastasia Hains, Elizabeth Brown, Emily G. Inwards, Angela K. Stoeckman, Mitchell P. Matis, Rebecca S. Sampathkumar, Natalia A. Osna, Kusum K. Kharbanda
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
lipid droplets
perilipins
phosphatidylcholine
phosphatidylethanolamine
steatohepatitis
Online Access:https://www.mdpi.com/2073-4409/7/12/230

Internet

https://www.mdpi.com/2073-4409/7/12/230

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