Resveratrol alleviates high glucose-induced oxidative stress and apoptosis in rat cardiac microvascular endothelial cell through AMPK/Sirt1 activation

Resveratrol alleviates high glucose-induced oxidative stress and apoptosis in rat cardiac microvascular endothelial cell through AMPK/Sirt1 activation

Diabetic cardiomyopathy (DCM) is a common complication of diabetes. DCM causes extensive lesions on cardiac microvasculature that is predominantly cardiac microvascular endothelial cells (CMECs). Reducing high glucose (HG)-induced damage such as oxidative damage and apoptosis could alleviate the dev...

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Bibliographic Details
Main Authors: Jinyu Li, Zikai Feng, Binger Lu, Xinzhe Fang, Danmei Huang, Bin Wang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Diabetic cardiomyopathy
Cardiac microvascular endothelial cell
Oxidative stress
Apoptosis
Resveratrol
AMPK/Sirt1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000250

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http://www.sciencedirect.com/science/article/pii/S2405580823000250

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