Optimized protocol for in vivo whole-cell recordings in head-fixed, awake behaving mice

Summary: This protocol describes stable in vivo recordings of neuronal membrane potential in awake behaving, head-fixed mice. Previous protocols often highlight the need to minimize animal movements by anesthesia or restraint. This protocol is optimized to minimize brain movements during animal moti...

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Bibliographic Details
Main Author: Rebecca Jordan
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672100054X