APOL1 and APOL1-associated kidney disease: A common disease, an unusual disease gene. Proceedings of the Henry Shavelle Professorship

Background: Genetic variants in APOL1 are a major contributor to the increased risk of kidney disease in people of recent African ancestry. Summary: Two alleles in the APOL1 gene, referred to as G1 and G2, confer increased risk of kidney disease under a recessive model of risk inheritance. Disease...

Full description

Bibliographic Details
Main Authors: Martin R. Pollak, David J. Friedman
Format: Article
Language:English
Published: Karger Publishers 2023-01-01
Series:Glomerular Diseases
Online Access:https://www.karger.com/Article/FullText/529227