Role of tumor draining lymph nodes in generation of memory CD8+ T cells in a murine model of colon cancer

Objective To investigate the role of tumor draining lymph nodes (TDLN) in the generation of memory CD8+ T cells under the context of neoadjuvant anti-PD-L1 therapy. Methods A mouse transplanted model of CT26/MC38-OVA colon cancer was established to recapitulate clinic neoadjuvant anti-PD-L1 therapy,...

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Bibliographic Details
Main Authors: XIE Shuanglong, ZHA Haoran, YANG Fei, ZHU Bo, LIN Zhihua
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-04-01
Series:陆军军医大学学报
Subjects:
Online Access:http://aammt.tmmu.edu.cn/html/202301077.htm