Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif.

Innate immune responses against DNA are essential to counter both pathogen infections and tissue damages. Mammalian EYAs were recently shown to play a role in regulating the innate immune responses against DNA. Here, we demonstrate that the unique Drosophila eya gene is also involved in the response...

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Bibliographic Details
Main Authors: Xi Liu, Teruyuki Sano, Yongsheng Guan, Shigekazu Nagata, Jules A Hoffmann, Hidehiro Fukuyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3419738?pdf=render