Alpha-1 Antitrypsin PI M Heterozygotes with Rare Variants: Do They Need a Clinical and Functional Follow-Up?

Alpha-1 Antitrypsin PI M Heterozygotes with Rare Variants: Do They Need a Clinical and Functional Follow-Up?

<b>(1) Background</b>: Few data are available on the risk of airway dysfunction in protease inhibitor (PI*) M heterozygotes carrying rare null or deficient allelic variants of the gene SERPINA-1 (PI*MR). <b>(2) Methods</b>: In this observational study, in a cohort of PI*MR he...

Full description

Bibliographic Details
Main Authors: Anna Annunziata, Giuseppe Fiorentino, Marco Balestrino, Roberto Rega, Sara Spinelli, Lidia Atripaldi, Alessio Sola, Federica Massaro, Cecilia Calabrese
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Clinical Medicine
Subjects:
alpha-1 antitrypsin deficiency
rare allelic variants of gene SERPINA-1
PI*M heterozygotes
spirometry
diffusing capacity of the lung for carbon monoxide
functional follow-up
Online Access:https://www.mdpi.com/2077-0383/13/4/1084

Internet

https://www.mdpi.com/2077-0383/13/4/1084

Similar Items