PfEMP1 A-Type ICAM-1-Binding Domains Are Not Associated with Cerebral Malaria in Beninese Children

ABSTRACT PfEMP1 is the major antigen involved in Plasmodium falciparum-infected erythrocyte sequestration in cerebrovascular endothelium. While some PfEMP1 domains have been associated with clinical phenotypes of malaria, formal associations between the expression of a specific domain and the adhesi...

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Main Authors: V. Joste, E. Guillochon, J. Fraering, B. Vianou, L. Watier, S. Jafari-Guemouri, M. Cot, S. Houzé, A. Aubouy, J. F. Faucher, N. Argy, G. I. Bertin
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02103-20