Effect of ursodeoxycholic acid on cholesterol absorption and metabolism in humans

Effect of ursodeoxycholic acid on cholesterol absorption and metabolism in humans

Qualitative and quantitative changes in intraluminal bile acid composition may alter cholesterol absorption and synthesis and LDL receptor expression. In a randomized crossover design outpatient study, 12 adults aged 24–36 years took 15 mg/kg/day ursodeoxycholic acid (UDCA) or no bile acid supplemen...

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Bibliographic Details
Main Authors: Laura A. Woollett, Donna D. Buckley, Lihang Yao, Peter J.H. Jones, Norman A. Granholm, Elizabeth A. Tolley, James E. Heubi
Format: Article
Language:English
Published: Elsevier 2003-05-01
Series:Journal of Lipid Research
Subjects:
cholesterol synthesis
low density lipoprotein receptor
luminal contents
bile acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520311391

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http://www.sciencedirect.com/science/article/pii/S0022227520311391

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